Aim: The purpose of our research was to assess the knowledge and awareness regarding infection control practice against coronavirus infection in various dental clinics in Saudi Arabia. Methodology: A descriptive survey was conducted amongst 200 dentists. The study was conceptualised in riyadh elm university, Riyadh, Kingdom of Saudi Arabia and inlcuded dentists from various dental clinics across kingdom of saudi arabia in the month of november,2020.  A questionnaire consisting of 12 questions was distributed, based upon knowledge of COVID-19, transmission as well as prevention strategies that can be implemented in dental clinics for stopping the chain of outbreak of this pandemic. The data was analyzed with the help of descriptive statistics using SPSS 25 software. Results: 71% of study participants felt the need for using N-95 masks routinely during patient treatment. An astounding number of participants (92%), believed that there have been significant changes in infection control after COVID-19 pandemic. 65% of participants believed that High volume evacuators (HVE) suction devices, as well as High efficiency articulate air (HEPA) filters, need to be used to control aerosol spread so as to prevent COVID-19 infection. Conclusion: Dentists in Saudi Arabia showed satisfactory knowledge and positive attitude towards COVID-19. Improving dentists’ level of knowledge could be achieved through increasing their accessibility to materials provided by dental health care authorities, which specifies the best and safest approaches for dealing with patients during and after the outbreak.