The aim of the study is to increase the morphological and functional status of cows depending on their physiologi-cal state. The morphological composition of blood is one of the main informative systems and has long attracted the attention of researchers. Blood, as a co-single tissue, has been studied well enough. Its indicators are the main fac-tors in determining the state of an animal health, as well as pointing out the presence of pathological processes in inside the organism. To determine the effect of complex use of STEMB (embryonic stimulator) and Uteromastin on the blood parameters of cows in comparison with individual administration three groups of pregnant cows (7.0-8.0 months) were formed separately, each with 20 heads in compliance with the method of groups-analogues (experimental-1, experimental-2, experimental-3). Animals in groups to be examined were provided the same con-ditions both in feeding and keeping. Animals of the first experimental group 25-30 days before calving were admin-istered STEMB drug hypodermic in the neck at a dose of 0.075 ml per 1 kg of live weight with an interval of 7 days three times, animals of the second experimental group were administered the drug Uteromastin 8-10 hours after calving intrauterine at a dose of 150 ml once. Cows of the third experimental group were administered drugs STEMB and Uteromastin in these doses (mixed). The influence of the complex use of drugs STEMB and Utero-mastin on morphological, biochemical and immunobiological parameters of blood of cows were studied on the 15th day after calving. The use of the drugs STEMB and Pteromalid complex improves cellular composition of the blood and indices of the blood serum, which enhances immunotoxicol system of organism of cows.

The aim of the research is increasing the productive indicators of replacement sheep of different genotypes by im-proving the interior indicators. To conduct the research, three groups of ewe hoggs with 20 heads each were formed: 1 group – ewe hoggs born from stud rams and Akzhaik ewes (AKSHM x AKSHM); 2 group – ewe hoggs born from stud rams of the North Caucasian breed and Akzhaik ewes (SK x AKSHM); 3 group – ewe hoggs born from Kuibyshev stud ram breed and Akzhaik ewes (KB x AKSHM). Blood parameters, live weight at the age of 4 and 8 months, hair cut at the age of 8 months was studied of animals of these groups. It was found that blood parame-ters of the ewe hoggs of different genotypes have significant differences and these affect the indicators of growth intensity and hair cutting. The content of red blood cells and hemoglobin of ewe hoggs from group 3 was higher by 0.551012/l and 9.32 g/l, respectively, than of ones from group 1. The biochemical blood parameters of crossbred ewe hoggs from groups 3 and 2 at 4 and 8 months of age in terms of total protein by 2.84 and 4.73 g/l, glucose – by 0.86 and 1.02 mmol/l exceeded the results of purebred Akzhaik ewe hoggs. Crossbreds of groups 2 and 3 in the 8-month age were superior to their herdmates of Akzhaik breed in live weight by 3.04 and 2.74 kg, and the washed wool cut – by 0.18 and 0.24 kg, respectively.

The aim of the study was to determine the etiopathogenesis of reproductive dysfunction in highly productive cows. Studies were conducted on cows of black-motley breed, aged 3–5 lactations, with a live weight of 480–520 kg. Cows were divided into two groups. The first group included 20 cows effective inseminated after the first insemination. The second group included 17 cows that did not fertilize after the first insemination. Blood samples (n = 253) were taken from 4–7; 14–17; 24–34; 35–50; 88–95; 195–210 days of pregnancy; during the beginning of dry period (DP); 1–4 days before calving and on the first day after calving. The content of total serum lipids in pregnant animals was 15.8% higher compared to unfertilized animals. In non-pregnant cows, a decrease in free cholesterol (by 28.65%), especially in its ether-bound fraction (14.91%), indicates a lower synthetic function of the liver, which is confirmed by the low serum levels of vitamins A and E (a difference of 11.3 and 23.65%). The DP was characterized by a significant increase in the products of lipid peroxidation - malondialdehyde by 12–17%, diene and triene conjugates - by 10–15 and 8–15%, respectively, and 1–4 days before calving in cows, which subsequently had a pathological calving, in particular - retention of placenta (5 cows), were characterized by an increased content in the blood plasma of lipid peroxidation products. Thus, the difference in the number of dienes, trienes, and malondialdehyde products was 14.0, 12.0, and 23.5%, compared with animals without obstetric pathology. On the first day after calving, this difference increased even more. Cows with retention of placenta had a significantly higher level of lipid peroxidation products and were characterized by a predominance of oxidized products over the antiradical thiol disulfide and ascorbate systems restored in the antioxidant balance.

The purpose of researches is to increase wool efficiency and quality of wool Akzhaiksky meat-wool breed of sheep due to purposeful use of new lines. Material for researches served Akzhaiksky meat-wool breed ewe of the BAK-4087 and ZKATU-7082 line. Both lines were created by method of difficult uniform and diverse selection of initial material that has allowed to receive animals of desirable type from which animals of the second generation from them by homogeneous and heterogeneous selection have been received selection for cultivation «in itself» has been made. Lines were created by taking into account wool efficiency and its quality indicators. In article comparative indicators of wool efficiency are considered it is bright the compared lines at 8-month age. By wool cutting in the original and free wool the ZKATU-7082 lines ewes are surpassed the contemporaries from the BAK-4087 line on 0.17 and 0.13 kg, respectively. From ewes BAK-4087 lines 64.0% of wool of the 56th quality and 16.0% – the 58th quality are received, and from it is bright the ZKATU-7082 lines 66.0% of wool of the 58th quality and 30.0% of wool – the 56th quality are received. Other wool by quality in the compared groups was the 50th quality. For indicators of natural and true length of wool and fortress of wool fibers the BAK-4087 lines authentically ewes are surpassed by ewes ZKATU-7082 lines. The obtained data can be the basis for improvement of wool efficiency of Akzhaiksky meat-wool breed sheep.

The purpose of researches is rising of efficiency of prophylaxis of cows patrimonial and puerperal pathologies. The current of cows labors and the puerperal period when using homeopathic medicine is studied Tsimaktin. It is estab-lished that drug Tsimaktin use reduces duration of cows current of labors in comparison with control by 1.87 hours. An involution of body and horns of experienced group uterus animals came to the end for 11.35 days earlier. Dis-turbances of involutional processes of control group cows reproductive organs to whom use didn't administer the drug 20% more Tsimaktin than at animals of experienced group. It is taped that drug Tsimaktin raises the morpho-functional status of cows organism that is confirmed by hematological and biochemical indicators of blood. The hemoglobin content, erythrocytes in control group cows blood after calvin was reliable less, than indicators of ani-mals of experienced group respectively on 15.09 g/l and on 1.94 1012 l. The indicator of the general protein in blood serum of experienced group cows is 2.69 g/l more than at cows of control group. The quantity of β-globulins after the delivery are more for cows of control group in comparison with experienced for 7,33% that indicates existence of inflammatory process in an organism of animals. Control group cows for 4-5 day the atsidotichesk state was after the delivery observed what the smaller indicator of an alkaline reserve on 3.38 ob%CO2 testifies to. Use of homeopathic medicine Tsimaktin in 25-30 days prior to labors allowed to raise cows fecundity and to reduce the number of days of sterility. Use of this drug is ecologically safe and allows to use milk without restrictions. On the basis of the conducted researches drug Tsimaktin can be recommended for prophylaxis of puerperal complications at cows.