In the first direction of this article, the new Marhamat, Mustaqillik-18 and Jararik-12 varieties of mulberry have economic value characteristics, such as leaf stem size, leaf length, leaf width, leaf stem length, leaf weight, leaf stem weight, leaf stem weight, and net leaf weight. In addition, the systems of mulberry silkworms Liniya-101 and Liniya-205 were cultivated with Marhamat, Jararik-12 and Mustaqillik-18 and Tajik seedless varieties of mulberry. The second direction of the study was the experiments on in vitro propagation of new varieties of tobacco, and the cost-effectiveness of testing in the conditions of production of positive data obtained on the basis of the results of 2017-2020. At the same time, it can be seen that the economic efficiency of mulberry varieties grown and introduced in vitro is 4,695,300 UZS, net profit is 1,577,500 UZS, and the size of profitability is 39.6% contrast to the comparator.