Unprecedented and unforeseen highly infectious Coronavirus Disease 2019 (COVID-19) has become a significant public health concern for most of the countries worldwide, including Nepal, and it is spreading rapidly. Undoubtedly, every nation has taken maximum initiative measures to break the transmission chain of the virus. This review presents a retrospective analysis of the COVID-19 pandemic in Nepal, analyzing the actions taken by the Government of Nepal (GoN) to inform future decisions. Data used in this article were extracted from relevant reports and websites of the Ministry of Health and Population (MoHP) of Nepal and the WHO. As of January 22, 2021, the highest numbers of cases were reported in the megacity of the hilly region, Kathmandu district (population = 1,744,240), and Bagmati province. The cured and death rates of the disease among the tested population are ~98.00 and ~0.74%, respectively. Higher numbers of infected cases were observed in the age group 21–30, with an overall male to female death ratio of 2.33. With suggestions and recommendations from high-level coordination committees and experts, GoN has enacted several measures: promoting universal personal protection, physical distancing, localized lockdowns, travel restrictions, isolation, and selective quarantine. In addition, GoN formulated and distributed several guidelines/protocols for managing COVID-19 patients and vaccination programs. Despite robust preventive efforts by GoN, pandemic scenario in Nepal is, yet, to be controlled completely. This review could be helpful for the current and future effective outbreak preparedness, responses, and management of the pandemic situations and prepare necessary strategies, especially in countries with similar socio-cultural and economic status.

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Water is a prime natural resource and precious national asset and one of the chief constituents of the environment. The chemical characteristics play a key role in terms of ecological and economic perspectives in the river water. The characterization and evaluation of river water quality in the Karmanasha River is necessary due to its immense importance in the livelihood of the people in the core urban areas of Kathmandu valley, Nepal. In this study, the surface water samples were collected from 16 sites with a 0.5 km interval to characterize and evaluate the water quality mainly from the perspective of its irrigational usage. The assessment was carried out by applying electrical conductivity (EC), sodium percentage (Na%), sodium adsorption ratio (SAR), permeability index (PI), Kelly’s ratio (KR), magnesium adsorption ratio (MAR), cation ratio of soil structural stability (CROSS), Wilcox diagram and water quality index (WQI) including the general hydrochemistry. The general hydrochemistry of river water indicates slightly alkaline in nature with mean pH value 8.07, and the dominance order of major ions follows the pattern of Ca2+>Mg2+>Na+>K+ for cations, and HCO3->Cl->NO3- for anions. Furthermore, the results revealed that the water is safe for irrigation purposes based on EC, Na%, SAR, KR, MAR, CROSS, and Wilcox diagram. The results also specified that no severe degradation in water, however, the low DO, and high BOD and COD values than that of the standard value prescribed by Nepal Drinking Water Quality Standard, signify the anthropogenic signature in the river water. This study provides the baseline information about the WQI and suitability of irrigation water quality, and further in-depth studies are required at spatiotemporal levels to get in-depth insights about the ecological health of the river.