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Plants are integral source of medicine in the rural areas, particularly in the tribal communities. An ethnobotanical survey on the medicinal plants used by the Gujjar community of the Trikuta hills, one of the least explored areas of the Jammu and Kashmir state of India, was undertaken. Information on the medicinal plants was mainly gathered from local people and traditional healers through questionnaires, and formal and informal discussions by undertaking frequent field trips. Seventy plants belonging to 43 different taxonomic families were recoded in the study area. Majority of the plants were herbs, though trees, shrubs, climbers and some epiphytes were also found. Leaves were ranked as the commonest part being used followed by roots and whole plants. More than one plant part was in use for the cure of different ailments. Most of these plants were used as decoctions, pastes, herbal teas or tonics and administered orally. Some of the plants encountered in the study area were rare and endangered thus inviting the attention for their conservation and preservation.

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Patience who suffered from menstrual pain disease is generally prescribed the non-steroidal anti-inflammatory drug (NSAIDs). Monorrhagia or another blood disorder & some gynecological disorder, which impairs body function and acts as an economic burden. Due to respective use of ACE by oral route, it may cause GI complication such as bleeding, pain, perforation, abdominal pain, and swelling. To decrease the side effect of ACE, it is given by topical route in promotes the safety & efficacy of the ACE. The Mefenamic Acid pharmacosomes were prepared by the hand shaking method technique and evaluated by various methods such as in-vitro release study, % yield, drug entrapment efficiency, pH of the prepared formulation. The prepared system was also characterized by FTIR spectrophotometer to identify the drug-excipients interaction. The maximum entrapment efficiency of pharmacosomes was found to be 90%. The main aim of this study was to develop and characterized a vesicular drug carrier system for topical delivery of Mefenamic Acid to overcome the problem related with oral route.