Extracts of Eurycoma Ion gifolia Jack (Simaroubaceae) have been tested for antiplasmodial activity against a multi-drug resistant Thailand strain (K-i) of Plasmodium falciparum in vitro. lO-Hydroxycanthin-6-one, eurycomalactone, eurycomanone and eurycomanol were isolated form the plant. The in vitro antimalarial activities of these compounds are reported together with that of 6-hydroxy-5, 6-dehydroeurycomalactone.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.