The knights who say Ni: A practical and convenient synthetic route to fatty acids involves the Ni‐catalyzed alkylalkyl cross‐coupling of bromoalkanoic acids and alkyl Grignard reagents in the presence of 1,3‐butadiene as an additive (see scheme).
Grignard reagents with long alkyl chains are difficult to handle requiring the reverse‐addition strategy of the Grignard reagents, generated in situ, to the tethered bromocarboxylic acids [viz.
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