Based on commonly quoted thresholds of society's willingness to pay per QALY of $50,000, the optimal approach in the Slovenian population would be screening women aged from 40 to 80 years every 3 years.

Although the large values of EVPI suggest collection of further information before choosing the screening policy, it is argued that delaying the decision would result in significantly higher opportunity loss. Therefore, the best option would be to implement the most cost-effective policy given the existing information (screening women aged 40-80 years, at 3-year intervals) and simultaneously conduct observational studies alongside the implemented policy. The decision analytic model could be in this manner periodically updated with additional information as it became available and the most cost-effective policy chosen iteratively.

Probabilistic uncertainty analysis reflects joint uncertainty across input parameters only when dependence among input parameters is accounted for.