A thiophene, two furans, a dihydro furan, and two acetylenic benzene derivatives were isolated from the roots of Eupatorium heterophyllum collected in China. Structures were established on the basis of spectroscopic analyses as well as chemical transformations.
Eight new hydroperoxides and a new enone of germacrane-type sesquiterpenoids were isolated from the aerial parts of eight different samples of Eupatorium heterophyllum DC. (Asteraceae) collected in P. R. China. The structures were determined based on spectroscopic analyses. Seven of the eight samples produced hiyodorilactone A as a major constituent, while one afforded neither hiyodorilactone nor hydroperoxide. The results indicated the presence of diversity within this species.
Germacranolides and Their Diversity of Eupatorium heterophyllum Collected in P. R. China. -[isolation and structure elucidation of 8 new hydroperoxyheterophyllin A-H (I)-(V) and one ketoheterophyllin A (VI)]. -(SAITO, Y.; MUKAI, T.; IWAMOTO, Y.; BABA, M.; TAKIGUCHI, K.; OKAMOTO, Y.; GONG, X.; KAWAHARA, T.; KURODA, C.; TORI*, M.; Chem. Pharm. Bull. 62 (2014) 11, 1092-1099, http://dx.doi.org/10.1248/cpb.c14-00426 ; Fac. Pharm. Sci., Tokushima Bunri Univ., Yamashiro, Tokushima 770, Japan; Eng.) -M. Bohle 20-266
The chemical constituents in the roots of 3 Cremanthodium campanulatum Diels (Asteraceae) samples collected in Yunnan and Sichuan Provinces, China, were chemically investigated. A total of 8 bisabolane-type sesquiterpenoids, 2 of which were new, and a new oplopane-type sesquiterpenoid, along with a new lignan were isolated and their structures elucidated based on spectroscopic analyses. This is the first report on the chemical study of C. campanulatum.
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