Multiple neuro-ophthalmological symptoms, such as visual field defects, optic neuritis, and eye movement abnormalities, have been reported with coronavirus disease 2019 (COVID-19) infection. It is unknown whether the COVID-19 vaccine can result in similar neuro-ophthalmological symptoms post-vaccination.Here, we describe a case of optic neuritis after the administration of the mRNA COVID-19 Moderna vaccine.A 47-year-old female presented eight days after receiving the first dose of the Moderna COVID-19 vaccine with impaired vision in the left eye and symptoms consistent with optic neuritis. The patient underwent a workup for infectious etiology, autoimmune diseases, and allergies, which was negative. The patient was treated with a high dose of steroids resulting in the complete resolution of her symptoms. The patient was recommended against the second dose of the mRNA COVID-19 vaccine.Early detection and treatment of optic neuritis are important to prevent the long-term sequelae of neuritis with impaired vision.

No abstract

Despite advances in treatment and prevention, malaria still carries significant morbidity and mortality. Cases of malaria in the United States are rare and cases of severe malaria, mostly attributable to Plasmodium falciparum , are even more uncommon. With the coronavirus disease 2019 (COVID-19) pandemic, there have been distractions in evaluation and diagnosis leading to a rise in cases and deaths. We present a case of autoimmune dysregulation and blackwater fever secondary to severe malaria, requiring multiple courses of antimalarial therapy. Careful travel history and prompt recognition and treatment facilitates improved patient survival and recovery.