No abstract

Viral infections have an essential function in both humans and other organisms. The persistent rise in viral diseases has made critical damage to human well-being. The present review indicates that viral diseases are been entangled in various cancer developments. Developing safe and effective antiviral medications remains a challenge. As a result, finding therapeutic targets that would interfere with the virus without affecting the host is hard-hitting. The use of natural substances rather than chemicals in the formulation of antiviral medications could significantly minimize the risk of side effects in patients. Coastal dune vegetation is a vital resource, which plays an imperative part in biodiversity. Coastal dunes have various utilizations in restorative and drug development. The drugs from marine are vitally been utilized as medicine due to their substantial antiviral, anticancer, and antimicrobial activities. Though Coastal dunes flora has numerous possessions their antiviral properties are rarely reported. Hence, in this report, we have compiled and highlighted the antiviral properties of 128 Indian coastal dune flora. This review may provide access to a profound understanding of coastal dunes’ vegetation resources and their usage in the production of antiviral and anticancer drugs. It may also help to preserve and cultivate these plants.

From the metabolite ecology (KNapSAcK) and herbs medicinal plants, phytochemistry, and therapeutics (IMPPAT) databases, the phytoconstituents from the herbal natural inhalant (turmeric) were taken. More samples of the phytoconstituents that adhere to drug likeness limits were obtained for in-silico research. To identify SARS-CoV-2 inhibitors, the Drug Likeness and ADMET experiments were used to screen volatile molecules from natural medicinal inhalants. The seven chemicals that make up turmeric all adhere to the ADMET restrictions and interact well with the Covid-19 proteins. Two active molecules are predicted by molecular docking studies to have strong binding affinity with the Sars-CoV-2 proteins (6LU7 and 6M0J). Based on this study 2 phytochemicals from turmeric, they have good binding affinity. DFT computing is applied to elucidate the molecular characteristics, and the molecular electrostatic potential (MEP) is generated to analyses the distribution of charges. These substances could be further subjected to in-vitro studies to evaluate their efficacy against Covid-19.