To our knowledge, the prevalence of Systemic Inflammatory Response Syndrome (SIRS) in pediatric patients with appendicitis has not been previously investigated. This study sought to determine the prevalence, test characteristics, and severity of illness of pediatric patient`s appendicitis and systemic inflammatory response syndrome (SIRS). Specific aim was to determine the prevalence of SIRS at the time and sings of presentation of pediatric patients with appendicitis. Additionally, we sought to determine if the presence of SIRS had any value in predicting their clinical outcome. The early definition of a systemic inflammatory response syndrome (SIRS) was built upon a foundation of basic clinical and laboratory abnormalities that were readily available in almost all clinical settings.

Mesenteric lymphadenitis is a disease that pediatric surgeons face on a daily basis due to symptoms resembling the symptoms of acute appendicitis. 45 children with abdominal pain were examined for the last 3 years, aged 3 to 18 years, treated non-surgically, and proven laboratory, microbiological and instrumental diagnosis. Mesenteric lymphadenitis is a very common diagnosis in children with suspected acute appendicitis. In previous methods, based solely on age and location, there were many difficulties in identifying the etiology of acute abdominal pain in children. We decided to develop a new systematic classification of acute abdominal pain. Carrying out a clinical and epidemiological analysis of the diseased children with acute surgical diseases in order to establish a pre-operative imaging and laboratory diagnosis, to establish the sensitivity of microbiological markers An overview of the literature on the topic has been made