A formal stereoselective synthesis of Herbarumin III has been accomplished starting from butanal involving Maruoka asymmetric allylation, diastereoselective iodine-induced electrophilic cyclization and conversion of iodocarbonate into syn-epoxy alcohol as the key steps.Nonenolide Phytotoxic effect Syn-epoxy alcohol Maruoka allylation Trimethylsulfonium iodide Diastereoselective iodine-induced electrophilic cyclization
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