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Approximately 250 cases of leiomyoma of the vagina have been reported. A case of a 46-year-old female with leiomyoma of the anterior vaginal wall, not associated with uterine leiomyomas is presented. The practical approach to such a vaginal mass entails immediate careful excision.

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Oestrogen replacement therapy either via oral or transdermal route has a beneficial effect on serum lipid profile of menopausal women. Whereas the oral route is more effective in increasing HDL cholesterol levels, the transdermal route is better for reducing the serum triglyceride level; hence, the latter should be the route of choice in women with high serum triglyceride levels.

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