Two iridoids, 7-deoxyloganic acid also known as bisdesoxydihydromonotropein and geniposidic acid, from Premna latifolia Roxb. (Verbenaceae) have been reported.

The aim of this study is to determine the antifungal activity of leaf and root extracts of Mimosa pudica against selected fungal pathogens Aspergillus terreus, Aspergillus flavus, Aspergillus niger and Fusarium solani by disc diffusion method. The solvents acetone, aqueous, benzene, diethyl ether and ethanol were used for the preparation of extracts from leaf and root of M. pudica. In this study, various concentrations of extracts 2.5 mg/50 μl, 3.75 mg/75 μl and 5 mg/100 μl were used and prepared discs individually for the determination of antifungal activity against selected fungal pathogens. The prepared discs were placed on each petriplate with respective fungal species along with control dimethyl sulfoxide (DMSO) and standard Iitraconazole (30µg) discs and then the plates were incubated at 27 ºC for 72 hrs. After incubation period, the diameter of zones formed around the discs was measured. The maximum levels of zone of inhibition were observed in ethanol root extract against Aspergillus flavus 20±0.8 mm, Aspergillus terreus 20±0.7 mm and acetone root extract against Aspergillus terreus 18±0.8 mm. The minimum level of zone of inhibition was observed in aqueous leaf extract against Aspergillus terreus 07±0.4 mm and acetone leaf extract against Aspergillus niger 07±0.8 mm. Minimum inhibitory concentration (MIC) of extracts of leaf and root of M. pudica against selected fungal species were also determined. In conclusion, there is in need of study to isolate and purify the active phytocompounds from leaf and root of M. pudica, which possess antifungal activity against above mentioned fungal species and it may be useful in the treatment of fungal diseases.