When studying iron deficiency as a cause of anaemia, the diagnostic cut-off for detecting deficiency should be higher than that used today. The ferritin level increases with inflammation and ought in practice to be considered in conjunction with the CRP level. The level of transferrin receptor in plasma increases with iron deficiency without being influenced by inflammation and is therefore a good supplement to ferritin measurement. Measurement of iron, transferrin and transferrin saturation provides little information additional to that provided by ferritin in iron deficiency studies.
The observed uncertainty indicates that Hemo_Control is appropriate for near patient testing using venous samples. Capillary samples may be used if sampling skills are adequate.
Tverrfaglig laboratoriemedisin og medisinsk biokjemi Akershus universitetssykehus Hun har videreutviklet førsteutkastet, gjennomgått litteraturen inkludert referansene og tilpasset manuskriptet til Tidsskriftets krav. Ingrid Marie Hardang (f. 1976) er overlege i medisinsk biokjemi. Forfatter har fylt ut ICMJE-skjemaet og oppgir ingen interessekonflikter. KRISTIN LILLEHOLT Avdeling for medisinsk biokjemi Sørlandet sykehus Hun har gjort litteratursøk, bidratt med utarbeidingen av manuskriptet og godkjent den innsendte manusversjonen. Kristin Lilleholt (f. 1966) er overlege i medisinsk biokjemi. Forfatter har fylt ut ICMJE-skjemaet og oppgir ingen interessekonflikter.
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