Although all subtypes of SK are benign, their association with other malignant lesions and ability to serve as cutaneous markers of internal malignancy emphasize the importance of correctly identifying all variants.

Background: Sarcoidosis is a systemic inflammatory disorder with cutaneous involvement present in 25% of cases. The presence of naked granulomas histologically is the hallmark of sarcoidosis. The presence of necrotizing granulomas is highly suggestive of other granulomatous conditions and leads the clinician to pursue other diagnoses, such as infectious causes.Objectives: We describe two cases of sarcoidosis in which necrotizing granulomas were present on biopsy. Both patients had ulcerated cutaneous lesions of sarcoidosis. In one case, the presence of these atypical histologic features led to a delay in diagnosis of almost 10 years. We review the various histopathologic findings associated with cutaneous sarcoidosis and discuss a potential connection between ulcerated sarcoidosis and atypical histologic findings.Conclusion: When atypical histopathologic features are present, the differential diagnosis of sarcoidosis should not be excluded.Contexte: La sarcoïdose est une affection inflammatoire gé né rale, accompagné e de lé sions cutané es dans 25% des cas. La pré sence, sur le plan histologique, de granulomes «nus» est le signe d'appel de la sarcoïdose. La pré sence de granulomes né crosants est fortement é vocatrice d'autres affections granulomateuses et incite les cliniciens à approfondir la recherche d'autres diagnostics possibles, tels que des infections.Objectifs: Seront dé crits ici deux cas de sarcoïdose, dans lesquels il y avait pré sence de granulomes né crosants à la biopsie. Les deux patients pré sentaient des lé sions cutané es ulcé ré es de sarcoïdose. Dans l'un des cas, la pré sence de ces aspects histologiques atypiques a mê me retardé de presque 10 ans la pose du diagnostic. Les diffé rents ré sultats de l'examen histopathologique, associé s à la sarcoïdose cutané e seront passé s en revue, et il sera question d'un lien possible entre la sarcoïdose ulcé rative et des aspects histologiques atypiques.Conclusion: Il ne faudrait pas é carter le diagnostic diffé rentiel de sarcoïdose devant la pré sence d'aspects histologiques atypiques.

Infliximab appears to be the most effective treatment for nail psoriasis to date.

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