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Breast cancer is the second most common malignant tumor worldwide and the most common oncological disease among women. This article presents our experience in postoperative Radiotherapy (RT) in 341 patients with Early Breast Cancer (EBC) after Breast-Preserving Surgery (BPS). Emphasis is placed on the indications and Clinical Target Volumes (CTV) for radiotherapy. The significant effect of postoperative RT in terms of Local Tumor Control (LTC), long-term recurrence-free survival and overall survival is reported. The main goal of this article is to establish high-tech radiotherapy after BPS in early BC as the main local method, optimizing the treatment and cosmetic results.

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