Taiwan and Japan initiated an industrial cooperation policy and incentive measures in 2011. Five Japanese prefectures in the Tokai Region actively communicated and cooperated with Taiwan after 2011. This motivated us first to address the economic and trade ties between Taiwan and Japan. Second, we compared and analyzed effects of the industrial cooperation policy on the five prefectures, their willingness to cooperate with Taiwan, and the topics brought up by the industry cooperation. Main results indicate that the policy offers positive incentives for industries and enterprises, and the cooperation between enterprises creates mutual benefits. In sum, the bilateral industrial cooperation brings about a win–win situation. With the findings, we make suggestions on future development direction and for the Taiwan–Japan industrial cooperation.
Aim: To mitigate assay interference in the drug and target assays to support the development of monoclonal antibody REGN-Z. Results: Mild acidic assay conditions and capture and detection antibodies with different affinities and t1/2 under different assay pHs were used to mitigate interference in the total drug and total target assays. A free target assay was also developed using a lower-affinity capture antibody with a much slower association and dissociation rate. The impact of sample incubation, dilution and storage on the accurate detection of the free target was also evaluated. Conclusion: The total drug, total and free target assays can accurately quantitate drug and target concentrations when tested with a subset of clinical study samples.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.