The aim of this study was to determine the effect of dietary cereal based fermented functional food (CBFFF) supplementation on growth performance, duodenum histomorphology, internal organ development and cecum microflora of quails. In this study, a total of 100 mixed sex birds at 21 age of days were used as animal material. The birds were divided into 2 dietary groups as control (C) and 5 g/kg CBFFF supplementation (F) with 5 replicates (5 male average 64.33±0.32g and 5 female average 66.42±0.38g for each replicate. The experiment lasted 21 days. Live weight gain (LWG), feed intake (FI), and feed conversion ratio (FCR) determined weekly. At the end of the experiment, one female and one male bird were selected from each replicate (a total number of 20 quails) and their characteristics of cecum microbiota and duodenum histomorphology were determined. LWG, FI, FCR, inner organs, did not change among the groups. Lactic acid bacteria (LAB) and yeast count was tend to increase, Enterobactericaea was tend to decrease. E coli and Coliforms count in cecum decreased statistically. Villi length increased in F group than in the C group. To conclude, CBFFF decreased pathogenic bacteria in cecum and developed intestinal microflora and increased the digestion surface area in duodenum. Therefore, it can be said that 5 g/kg dietary CBFFF can use to improve cecum microflora and duodenum histomorphology in quails. But further studies should be conducted to determine probiotics effects of CBFFF on other animal species, doses or stress factors such as feed restriction, high fiber or low protein in diet etc.