Objective: To investigate the diagnostic value of duplex ultrasound in the diagnosis of liver tumors. Method: The present study included 152 cases of liver tumors; there were 87 malignant and 65 benign tumors. Visualization of liver tumors was carried out of duplex ultrasound using a convex transducer in the frequency range of 2-5 MHz on Philips HD-11. The p-value <0.05 was regarded as having a significant difference. Results: The hepatocellular carcinoma was diagnosed in 29 cases, the cholangiocellular carcinoma – in 21 cases, the metastatic liver cancer – in 37 cases, the capillary hemangioma – in 39 cases and the cavernous hemangioma – in 26 cases, respectively. In 115 cases (P<0,001), liver tumors were localized in the right lobe, in 37 cases – in the left lobe. In 59 cases, the tumor morphology was regularly, in 93 cases – irregularly. In 74 cases, the tumor boundary edge was clearly, in 78 cases – unclearly. Acoustic halo at the edge of the tumors was observed in 27 cases, of which HCC in 19 (65.5 ± 8.8%) cases (P<0,001). Isoechoic lesions were registered in 19 cases of liver tumors, of which in 11 (52.4±10, 9%) cases of cholangicarcinoma – significantly (P<0.001) higher than the rest. Conclusions: Duplex ultrasound allows you to identify the malignant and benign liver tumors. The most significant ultrasonographic signs of malignancy of the formation are fuzzy contours, heterogeneous internal structure, hypoechogenicity and increased vascularization of the pathological formation