For the aim of discovering new fungicide, a series of phenylpyrrole-substituted tetramic acid derivatives bearing carbonates 6a-q were designed and synthesized via 4-(2,4-dioxopyrrolidin-3-ylidene)-4-(phenylamino)butanoic acids 4a-k and the cyclized products 1 1 ,3,4,5 1 -tetrahydro-[2,3 1 -bipyrrolylidene]-2 1 ,4 1 ,5(1H)-triones 5a-k. The compounds were characterized using IR, 1 H-and 13 C-NMR spectroscopy, mass spectrometry (EI-MS), and elemental analysis. The structure of 6b was confirmed by X-ray diffraction crystallography. The title compounds 6a-q were bioassayed in vitro against the phytopathogenic fungi Fusarium graminearum, Botrytis cinerea and Rhizoctonia solani at a concentration of 100 µg/mL, respectively. Most compounds displayed good inhibitory activity.