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BackgroundMicropapillary variant of urothelial carcinoma (MPUC) showed distinct pathologic features and aggressive behavior. The cytologic findings of MPUC are still indistinct. In this study, we evaluated the cytological findings of MPUC compared with those of high-grade urothelial carcinoma (HGUC).MethodsThe voided urine cytology of 8 cases of MPUC and 8 cases of HGUC was reviewed. Following cytological parameters were evaluated: cellularity, background, number of small, tight papillary clusters, small acinar structure, scattered single cells, cytoplasmic features, nuclear-to-cytoplasmic ratio, nuclear pleomorphism, nuclear membrane irregularity, hyperchromasia, chromatin pattern and nucleoli.ResultsCompared to that of HGUC, cytology of MPUC showed large numbers of small, tight papillary clusters, small acinar structure, few numbers of single cells, and hyperchromatic nuclei. Other parameters were similar between the two groups; both groups showed similar cellularity, dense or vacuolated cytoplasm, moderate to severe nuclear pleomorphism, irregular nuclear membrane, coarse granular chromatin, and small and prominent nucleoli.ConclusionsThe urine cytology of MPUCs showed smaller and tighter papillary cell clusters, more small acinar structures, fewer numbers of scattered single cells, and more hyperchromatic nuclei than that of HGUC. These features can help to distinguish MPUC and HGUC and offer an early cytological diagnosis of MPUC.

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To ensure the frequency stability of a power grid, the settling frequency following a frequency event should be stabilized within the maximum steady-state frequency deviation (SSFD) band. If the frequency is stabilized at a value beyond the maximum SSFD band for high penetrations of variable renewable energy, the frequency cannot be restored to the nominal frequency because automatic generation cannot be activated. This paper proposes a primary frequency control support scheme of a doubly-fed induction generator (DFIG) to improve the settling frequency following an event. In the proposed scheme, if the frequency following an event is stabilized at a value beyond the maximum SSFD band, to reduce the output power of synchronous generators, the output power of a DFIG is instantly increased by a constant and maintained until the frequency increases to within the maximum SSFD band. At the same time, the mechanical input power of the synchronous generators is maintained so that the difference between the mechanical input power and electrical output power of the synchronous generators increases the frequency to a value within the maximum SSFD band. The simulation results demonstrate that the proposed scheme can improve the settling frequency while avoiding additional system defense plans when the settling frequency is stabilized at a value beyond the maximum SSFD band.

-This paper presents a generation rescheduling method for the enhancement of transient stability in power systems. The priority and the candidate generators for rescheduling are calculated by using the energy margin sensitivity. The generation rescheduling formulates the Lagrangian function with the fuel cost and emission such as x NO and x SO from power plants. The generation rescheduling searches for the solution that minimizes the Lagrangian function by using the Newton's approach. While the Pareto optimum in the fuel cost and emission minimization has a drawback of finding a number of non-dominated solutions, the proposed approach can explore the non-inferior solutions of the multiobjective optimization problem more efficiently. The method proposed is applied to a 4-machine 6-bus system to demonstrate its effectiveness.