Adenoid cystic carcinomas of the Bartholin’s gland are extremely rare and are often misdiagnosed. There are currently no definite treatment guidelines. This article describes the case of a 33-year-old female who was managed at our centre for adenoid cystic carcinoma of the Bartholin’s gland. She presented with a prolonged history of a vulvar lesion which was eventually diagnosed as adenoid cystic carcinoma of the Bartholin’s gland. She was subsequently treated with wide local excision of the primary and inguinal lymph node dissection followed by adjuvant radiotherapy and chemotherapy. She had gross perineural invasion on MRI imaging. The present case highlights the diagnostic dilemma in this extremely rare cancer and the literature further explores the natural history and treatment options.

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This is one of few studies of preanalytical nonconformance in a medium-sized private laboratory setting. Monitoring nonconformance for a pathology laboratory is essential to determine areas where further improvements can be made.

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count (FBC), haemoglobin electrophoretogram (HbEPG) and genetic test results for women and their partners. Comparison of laboratory results observed before (Jan 2015 -Aug 2018, n=613) and after (Sept 2018 -Dec 2020, n=416) implementation of the algorithm.Results: Use of the screening algorithm resulted in a 15% shift towards identification of clinically significant results, despite a 48% reduced demand on the molecular laboratory. The number of one gene HBA deletions referred was reduced by 50%, with a relative increase in the detection of two gene deletions (in cis) by 15%. The distribution of FBC and HbEPG indices applied in the algorithm was maintained in the post-implementation cohort. The collaboration between molecular and haematology laboratories in the design of this algorithm resulted in improved patient care and laboratory resource management.