The article examines the regulators of plant growth and development, their properties and influence on living organisms. The new evaluated preparation with the trade name “Cresolan” was studied and tested at the central experimental field at the “Uralets”, the educational farm of the Ural State Agrarian University. Various doses, periods, methods of use, combinations and its comparison with other similar preparations were studied (the experimental tests were carried out on spring wheat of the “Iren” variety and barley of the “Ecolog” variety). The spring wheat and barley plants showed great responsiveness to the preparation. According to the research results, a significant increase in the productivity and resistance of the studied grain crops was revealed, due to the increasing adaptive abilities of plants to the effects of unfavorable environmental factors. It was also concluded that it is necessary to generalize the material and to study some more issues for the development of an adapted technology of application of the plant growth and development regulator “Cresolan”, which ensures stable efficiency.