Earthquakes can lead to different levels of damages and subsequently produce significant volume of debris. Management of such huge amount of debris needs special attention. Thus, it is vital to develop a comprehensive and cost-effective management plan. The present study was carried out to estimate post-earthquake debris volume in the 22 districts of Tehran under various earthquake scenarios [magnitudes of 5, 6.5, and 7.5 on the moment magnitude (M W ) scale]. Subsequently, required machineries and manpower and equipment for removal of debris were calculated. Finally, best practical methods for reduction and recycling were also examined. The shortest routes for transportation of post-earthquake to disposal sites were also proposed using network analysis. Results showed that about 83, 321 and 4802 million cubic meters of debris will be generated at 5, 6.5 and 7.5 M W , respectively. Disposal site of about 13 km 2 is marked within the area of study for the management of debris. Preparedness, emergency operations, rehabilitation and reconstruction are among the main activities that can reduce the earthquakeinduced damages.