Baculoviruses are insect viruses largely used as expression vectors and biopesticides. These viruses can efficiently infect the larval stage of several agricultural pests worldwide causing a lethal disease. In this work, we found a novel baculovirus isolated from the larval stage of Urbanus proteus (L.), the bean leafroller and characterized its complete genome. This is an important pest of several leguminous plants in Brazil and belongs to the butterfly family Hesperiidae, from where no baculovirus genome sequence has been described. This new virus was shown to have the smallest genome among all alphabaculoviruses sequenced to date, with 105,555 bp and 119 putative ORFs. We found ten unique genes, seven bro, and the 38 baculovirus core genes. UrprNPV was found to be related to the Adoxophyes-infecting baculoviruses AdorNPV and AdhoNPV with high genetic distance and a long branch length. Interestingly, few individual core gene-based phylogenies were found to support the relationship of UrprNPV to both AdorNPV and AdhoNPV. Importantly, the increase in number of completely sequenced baculovirus points to a very exciting way to understand baculovirus and its evolution and could potentially help the use of baculovirus as both biopesticides and expression vectors.
A suplementação de beta-alanina tem sido amplamente utilizada como um suplemento alimentar para melhorar o desempenho físico. Seus efeitos positivos estão associados ao aumento da carnosina muscular, que proporciona maior resistência e redução da fadiga durante os treinos em diferentes modalidades esportivas. Posto isso, este artigo tem como objetivo apresentar uma revisão bibliográfica narrativa que explora os benefícios da suplementação de beta-alanina no desempenho esportivo e sua influência na composição corporal. A revisão também enfoca o papel da beta-alanina na formação da carnosina, um composto dipeptídeo presente naturalmente no corpo humano. Os resultados destacam que a beta-alanina apresenta benefícios no desempenho físico, com apenas um efeito colateral facilmente evitado, contribuindo para a melhoria da resistência e redução da fadiga muscular durante os treinos de resistência. Os estudos investigados demonstram que a suplementação de beta-alanina contribui para o melhor desenvolvimento do exercício, elevando os níveis de carnosina e minimizando a sensação de fadiga, resultando em aprimoramento do rendimento físico.
The measurement of multiple interfaces is particularly important for the oil companies, because the crude oil from the sea floor contains a significant amount of water. The paper's aim is to improve this process by the use of virtual sensors for inference these interfaces, once there is a great difficulty by physical sensors. This paper presents two approaches of the Kalman Filter and data fusion for developing a soft sensor to estimate the oil-water interface of an oil separator. The results of numerical simulations, based on the model of a three-phase separator unit, show the effectiveness of the methodology and its potential for the applications in real systems. Keywords Level sensors, soft sensors, Kalman filter, data fusion. Resumo A medição de múltiplas interfases é particularmente importante para as companhias de petróleo, porque o óleo bruto
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