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SynopsisTwenty-seven chronic schizophrenics and nineteen controls, all male, were evaluated by computed tomography (CT) scans. Lateral, third and fourth ventricles and cerebral density numbers were measured. In the schizophrenic patients there was a significant increase in third ventricle width. Ventricular Brain Ratio (VBR) and there were significantly higher densities of white matter in the right frontal and parietal region.