Synthesis and Immunostimulating Activity of New 1,4-Benzothiazine Derivatives.-Title compounds such as (III) (11 examples) and (VI) are prepared and tested for their immunomodulating properties. All the products show activity in superoxide anion production by peritoneal macrophages in prednisolone-immunodepressed mice. The most interesting compounds ( IIIa), (IIIb) and (VI) are studied in comparison with standard ( Roquinimex) in the same test at lower dosages. The results show that ( IIIa) and (VI) are more active than Roquinimex. -(DEL CORONA, L.; SIGNORELLI, G.; PINZETTA, A.; COPPI, G.; Eur.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.