Since Miller's experiment in 1951, research on prebiotic chemistry has received much attention of chemists. However, there are a few lines of research with the focus directed to this science in Brazil. Therefore, the objective of this paper is to describe some of the research in this field, with emphasis on peptide synthesis under prebiotic conditions and the implication of these studies in the context of molecular enrichment on the primitive earth. We also want to encourage new researchers conducting research in this area as well as promoting scientific debate related to the topic of the origin of life.Keywords: Prebiotic chemisty; peptides; astrobiology in Brazil. ResumoDesde o experimento de Miller em 1951, a pesquisa em química pré-biótica tem recebido muita atenção dos químicos. No entanto, existem poucas linhas de pesquisa com o enfoque direcionado a esta ciência no Brasil. Assim, o objetivo deste artigo foi descrever algumas das pesquisas neste campo, com ênfase na síntese de peptídeos em condições pré-bióticas e a implicação destes estudos no contexto do enriquecimento molecular na terra primitiva. Desta forma, pretende-se incentivar novos pesquisadores a desenvolver pesquisas nesta área, bem como promover o debate científico relacionado com o tema da origem da vida.Palavras-chave: Química pré-biótica; peptídeos; astrobiologia no Brasil.
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