This clinical profile of SIPD could help to facilitate the accurate diagnosis and treatment of SIPD versus PPD in young people with first episode psychosis admitted to an inpatient psychiatric service.

16s S09. Is schizophrenia really just a neurodevelopmental disorder? as in the normal elderly population. Antipsychiotics and most antidepressant medications impair sexual function even further, leading to non-compliance and relapse. The prevalence of sexual dysfunction in schizophrenics treated with typical and atypical antipsychotics is 30-60%. Attempts to treat sexual dysfunction using dopaminergic drugs such as L-dopa, apomorphine, amantadine and L-deprenyl were disappointing. Sildenafil citrate (Viagra) seems to be an effective treatment in less deteriorated male patients who are capable of maintaining a reasonable relationship with their partners. A variety of strategies have been used in the management of SSRIinduced sexual dysfunction: waiting for spontaneous resolution, dosage reduction, drug holidays, adjunctive pharmacotherapy or switching antidepressants. Adjunctive agents are SHTr antagonists (cyproheptadine, mianserin, mirtazapine), dopamine receptor agonists @sychostimulants, bupropion) and Viagra. Substitute antidepressants are bupropion, nefazodone, mirtazapine and reboxetine. In an open-label study with 10 male SSRI-treated PTSD patients who complained of sexual dysfunction, the use of sildenaIi1 (50 mg) significantly improved their erectile function and intercourse satisfaction. Sildenafil (25-50 mg) was efficacious also for antidepressant-induced erectile dysfunction in elderly male depressed patients (n=ll, age 70-81, mean age 73 yrs). In 8 out of 11 patients, erectile function returned to a normal level. Side effects were noted in two patients (headache). It appears that sildenafil co-administration is efficacious, safe, and well-tolerated in special populations. S09. Is schizophrenia really just a neurodevelopmental disorder?