Purpose. To define relevant problems and propose ways for development of production, scientific and educational spheres associated with nuclear-and-fuel power industry of Ukraine. Methods.The current state of uranium and zirconium production, as well as accompanying enterprises has been analyzed. Issues related to training of workers, engineers and highly-qualified personnel are considered in the context of implementation of the State target economic program "Uranium of Ukraine". Findings.The impediments in the development of production, scientific and educational spheres on the way of creating the closed nuclear-and-fuel cycle in Ukraine are determined.Originality. The author suggests forming an administrative inter-branch body with pedagogic and research functions that will be able to successfully solve production, scientific and educational problems in structural units of nuclearand-fuel cycle of Ukraine.Practical implications. The paper laid the groundwork for creating a corporate educational institution of power engineering profile in Ukraine which will solve pivotal problems in production, scientific and educational spheres of nuclear-and-fuel cycle.