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Львівський національний медичний університет імені Данила Галицького Ориґінальні дослідженняSimilar associations were also revealed by the results of analysis of relationship between bone mineral density and GC treatment, which was measured by the average dose ((r = (-0.59), p < 0.001) and the total dose ((r = (-0.52), p < 0.001).Conclusions. The analysis of the effect of SLE selected indicators and its treatment on bone mineral density revealed that: 1) the percentage of women with decreased bone mineral density was significantly higher in the treatment group than in the control group (lumbar spine DXA scans -75.7 % (35.5 %), proximal femur DXA scans -35.5 % (16.0 %), respectively), and the average T-scores for lumbar spine scans were significantly lower in patients with SLE than in the control group -(-1.41) ± 1.15 and (-0.55) ± 0.99, respectively. 2) there is no reliable correlation between bone mineral density and the disease activity according to SLEDAI; 3) there is a inverse relationship between the bone mineral density and SLICC / ACR Damage Index, the duration of disease, the total number and duration of SLE exacerbations, as well as the total dose of glucocorticoids.

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