Monarda fistulosa essential oil characterized by pronounced therapeutic effects is proposed for the treatment of seborrhea. Studies of its antibacterial, antimycotic, and antiinflammatory activities showed that it inhibits microorganism growth and is superior to hydrocortisone in combination with vitamin B6 by its antiinflammatory activity.

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The article is devoted to the consideration of the possibility of using fullerene-containing water as part of humic growth-stimulating preparations for agriculture with the addition of yeast production waste. More recently, the problems of the economy and the environment were perceived as opposite. Currently, there is a need for a mutually dependent and mutually beneficial combination of economic and environmental interests, which was the basis for this study. The analysis of the wastewater of the yeast-producing enterprise shows the presence of a large number of chemical and organic substances that pose a certain danger to the environment, but are useful after processing waste for use in agriculture. The largest number of substances is found in waste, after the stage of production of pure culture. The experiment shows that the use of structured water in combination with biologically active waste from the production of bread yeast obtained on the basis of the Saccharomyces cerevisiae strain increases the yield of grain crops. Based on the established fact of a wide and universal spectrum of biological activity of the water-carbon structure of hydrated fullerenes, according to patent and scientific and technical literature, they have not been widely tested as plant growth regulators. We will investigate the interaction of substances with water structured with fullerenes, the effect of surfactants on the formation and stability of emulsified humates with film-forming agents, the adhesive properties of the components, the effect of concentrated yeast fermentation liquid separated after the stage of growing a pure culture of baking yeast, the effect of both a fullerene-like structure – shungite of natural origin and hydrated fullerenes – highly stable finely dispersed aqueous solutions of native fullerenes (have the properties of lyophobic molecular colloidal systems) on grain yield, protection of vegetative plants. The result of the work will be the substantiation of the principles of the methodology for the application of nanostructured substances for use in biotechnologies of multifunctional highly effective drugs for agriculture with biologically active additives.

The aim of the study was to determine the degree of antimicrobial activity of the anthocyanin complexes of Aronia melanocarpa (Aronia melanocarpa), black currant (Ribes nigrum), elderberry (Sambucus nigra) with reference culture Staphylococcus aureus ATCC 25923, Escherichia coli АТСС 25922, Bacillus subtilis ATCC 6633, Pseudomonas aeruginosa АТСС 27853, Candida albicans NСTC 885-653. The highest degree of microbiological sensitivity of bacterial cultures Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa was observed in the native form of anthocyanin complexes derived from black currant (Ribes nigrum), Escherichia coli and Bacillus subtilis-to the anthocyanins in native form, derived from elder black (Sambucus nigra), which indicates their high antimicrobial activity against the microorganisms mentioned above. Reducing the concentration of anthocyanins in alcoholic extract at dilution in the ratio of 1:1 and 1:2 significantly decreased the microbiological sensitivity of microorganisms to them Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomonas aeruginosa. When surveying the effects of anthocyanin complexes from Aronia melanocarpa, Ribes nigrum, Sambucus nigra on Candida albicans fungi culture, no sensitivity was established, which indicates the absence of antimycotic activity of the above complexes in laboratory conditions in vitro.