detectable by PCR in PBMC. If such is indicative of active infection, 30% of healthy individuals would be having active HHV-7 infection at any one time point.In summary, we compliment Vág et al. in having reported a high-quality study with a novel approach, but are unconvinced that their results provide conclusive evidence of recent primary HHV-7 infection in young adults with PR. References1 Vág T, Sonkoly E, Kárpáti S, Kemény B, Ongrádi J. Avidity of antibodies to human herpesvirus 7 suggests primary infection in young adults with pityriasis rosea. J Eur Acad Dermatol Venereol 2004; 18: 738 -740. 2 Kosuge H, Tanaka-Taya K, Miyoshi H et al. Epidemiological study of human herpesvirus-6 and human herpesvirus-7 in pityriasis rosea. Br J Dermatol 2000; 143: 795-798. 3 Yasukawa M, Sada E, Machino H, Fugita S. Reactivation of human herpesvirus 6 in pityriasis rosea. Br J Dermatol 1999; 140: 169 -170. 4 Chuh AAT, Chiu SSS, Peiris JSM. Human herpesvirus 6 and 7 DNA in peripheral blood leukocytes and plasma in patients with pityriasis rosea by polymerase chain reaction -a prospective case control study. Acta Derm Venereol 2001; 81: 289-290. 5 Chan PK, Peiris JS, Yuen KY et al. Human herpesvirus-6 and human herpesvirus-7 infections in bone marrow transplant recipients. J Med Virol 1997; 53: 295 -305. 6 Vág T, Sonkoly E, Kemeny B et al. [Studies on the novel association of human herpesvirus-7 with skin diseases.].