One of the main problems which arise employing PDT is the patients sensitization to the sunlight during 4-6 weeks period after i/v photosensitizers injection. Applying PDT for the patients with head and neck cancer there is often the possibility to inject photosensitizer (there were used the doses of photosensitizer many times smaller than in ordinary PDT) was injected intraarterial (i/a). This was followed by the immediate tumor irradiation with laser light. The absorbed light's energy dose was the same as the dose usually used during the PDT.Since 1989 172 head and neck tumors were treated by us applying ordinary PDT and for 17 foci of oral cancer we provided intraarterial photodynarnic therapy. The result of i/a PDT was the same, as in usual usage of PDT. But i/a PDT enables the usage of much smaller doses of photosensitizer. Patients need not to be protected from the sunlight. Jia PDT enables us also to use effective but quickly spitting photosensitizers.
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