The possibility of using natural or modified polymers to formulate drug-containing nanocapsules is a pharmaceutical option for cases in which an increase in the half-life of medications in the body and a decrease in side effects is required, and may also be used for better pharmacological targeting of the site. Related to low production costs with these characteristics and renewable availability. Gums and mucilages have been studied for use in natural alternative drug delivery systems. The gum from the trunk of Mangifera indica has few studies aimed at this purpose, although it has shown promising results in previous studies. Characterization of the gum formation pathways are explained, as well as their extraction and purification. The similarity of properties of Acacia gum widely used in tablet blends has been confirmed. Mangifera indica gum was also used for accelerated drug release. The versatility of this gum is associated with the presence of mucilage. Chemical modifications of the Mangifera indica gum and mixtures among other gums may be made to adapt their properties to the various forms of controlled drug release. Several isolated compounds with pharmaceutical properties are demonstrated. Physical chemical characteristics of several articles on this gum have been compiled. The techniques already used for the formation of nanocapsules through Mangifera indica gum are presented. Several studies have been reported specifically using Mangifera indica gum from the Mango trunk used as drug release. These studies justify a summary of the pharmaceutical properties for drug delivery already performed with this gum. Complementary studies for utilization and valorization of Mango cultivation are suggested.

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