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Introduction: Kidd blood group system has a special importance in transfusion medicine as the antibodies to Kidd antigens tend to go down to undetectable levels but show an anamnestic response on exposure through pregnancy or blood transfusion and cause hemolytic transfusion reaction, most commonly delayed transfusion reaction. Case Report: We report a patient who developed alloantibodies to 'Kidd a' antigen leading to delayed hemolytic transfusion reaction. Conclusion: We emphasize the steps for detecting these antibodies and the precautions to be taken once these antibodies are identified.

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