A systematic study has been conducted for the regioselective halogenation of 2H‐chromenones to prepare 3‐halo‐2H‐chromenones, 4‐substituted 3‐halo‐2H‐chromenones and 3‐(2‐haloacetyl)‐2H‐chromenones. Commercially available NaCl/NaBr has been used as halogen source and oxone as an oxidant to produce the compounds. Further, the method has been successfully applied for the preparation of pharmaceutically important halogenated 2H‐chromenone natural products. The present approach is simple, economically viable and provided the target compounds with good yields.