This study examines the commercialization strategy implemented by one of the Indonesian government research institutes Agency for the Assessment and Application of Technology (BPPT) as an effort to commercialize the results of technological innovation products to increase competitiveness towards national independence. This research explains how BPPT encourages the manufacture of product and service technology through of creating innovations by developing effective strategies to commercialize technology products, how the implementation of business processes and the incubation process products. This study used a qualitative method with case study approach. The results found that BPPT launched commercialization strategy by focusing on creating technology innovation products market driven that support industrial needs. The success of product marketing is because BPPT already had users that matched the institutional targets. Other findings found that business process consists of ten stages: research, technology disclosure, assessment, intellectual property protection, technology marketing, selecting the best partner, cooperation agreement, project management, payment and royalties, and reinvest. The commercialization of technology products from research institute is more successful if supported by well preparation, planned and measurable strategic plan, so strategies in increasing the role of technology through innovation and technology services will be in line with the direction of national development.