In a Fresnel-based Concentrated Photovoltaic system, multi junction solar cells suffer from increased PV temperature, resulting in a decrease its electrical efficiency. This study design to investigate the influence of using Water/Al2O3 Nanofluid as cooling fluid on heat transfer enhancement and top surface temperature for multi-junction solar cell in the Fresnel-based Concentrated Photovoltaic thermal CPVt System. The CFD simulation was conducted on mini-channel under the concentrated multi-junction solar cell with using water/Al2O3 Nanofluid and pure water as coolant fluids. The Reynolds number is in the range of 15000-30000 were examined. The average Nusselt numbers augmented through increasing Reynolds numbers. The water/Al2O3 Nanofluid provides highest heat transfer enhancement of 23% compare with water in Fresnel-based CPVt system. The top surface temperature decreases as Nusselt number increases. The Nuavg improves 21% with using of water/Al2O3 Nanofluid at lowest Reynolds number of 15000 and 23% at highest Reynolds number of 30000.The top surface temperature dropped from 337K to 327K at lowest Reynolds number of 15000 with using Water/Al2O3 Nanofluid as cooling fluid and from 323K to 315K at highest Reynolds number of 30000.This study has confirmed that the use of water/Al2O3 Nanofluid has significant influence on the dissipate the heat from Multi-Junction Solar Cell in Fresnel-based CPVt system which led to improve its electrical efficiency.

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