The study on the resistance of different wetland plants to wastewater duress is the key to ecological wastewater treatment technology. This paper studies the change of soluble protein content in 4 common wetland plants (Phragmites communis, Typha angustata, Arundo donax and Canna generalis) in Shandong in different wastewater duress time. The results show: when the wastewater duress time is 2 days and 4 days, soluble protein content in Phragmites communis has minimal change, and its anti-stress capability is the strongest; when the wastewater duress time is 6 days, soluble protein content in Canna generalis has minimal change, and its anti-stress capability is the strongest, followed by Typha angustata.