This was a mixed methods study designed to examine the perceptions of young adults with autism spectrum disorder (ASD) regarding usage of computer-mediated communication (CMC), with a focus on benefits, challenges, and support needs. People with ASD are often prone to social and communication difficulties, making it difficult for them to maintain relationships, find and retain employment, and be active members of their communities. Deficits in these areas are particularly hard for young adults who may no longer have regular routines or opportunities for socializing because they have transitioned out of school-based activities. CMC is a relatively new form of communication, but research suggests its benefits are nearly the same as face-to-face communication for people in the general population. Quantitative and qualitative data obtained from the online survey and interviews indicate overall more perceived benefits than challenges, with suggestions for supports. Overall findings suggest that flexibility in responding is of value to young adults with ASD, while fear of loss of privacy is a challenge in utilizing CMC. Implications for future research include finding ways to help mitigate challenges, and use of explicit instruction regarding CMC tools for those on the spectrum.