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The BDS is easy to use and provides good levels of sensitivity and specificity.

Restriction fragment length polymorphism analysis of environmental (pigeon excreta) and clinical Cryptococcus neoformans var. neoformans isolates in a limited geographic area distinguished 6 strains among 8 environmental isolates and 12 strains among 17 clinical isolates. Clusters of patients with three strain types accounted for 47% of clinical isolates. Despite this diversity, two strains were shared by environmental and clinical isolates.

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