ORIGINAL PROF-3025ABSTRACT… Infertility is very stressful event and is proven to associate with depression, anxiety, sexual dysfunction loneliness, sadness and impaired couple's relationship. Objectives: To determine the frequency of depression in infertile females and to determine the various risk factors associated with infertility and depression. Study Design: Prospective cross sectional study. Setting: Department of Obstetrics and Gynecology of Ziauddin University Karachi. Period: January to June 2014. Methodology: Infertile women were interviewed and the diagnosis and severity of depression was assessed together with the effects of different predicators such as age, duration of infertility, employment educational and socioeconomical status using PHQ-9 scale scoring. Results: This study showed that 199 (58%) of the infertile women suffered from depression. There was a statistically significant association with socio economical status while no significant association was detected with age of women, duration of infertility and educational status. Conclusion: We found a high prevalence of depression among infertile women. Depression was more among women belonging to higher socioeconomic class.

Infertility is very stressful event and is proven to associate with depression,anxiety, sexual dysfunction loneliness, sadness and impaired couple’s relationship. Objectives:To determine the frequency of depression in infertile females and to determine the various riskfactors associated with infertility and depression. Study Design: Prospective cross sectionalstudy. Setting: Department of Obstetrics and Gynecology of Ziauddin University Karachi. Period:January to June 2014. Methodology: Infertile women were interviewed and the diagnosis andseverity of depression was assessed together with the effects of different predicators such asage, duration of infertility, employment educational and socioeconomical status using PHQ-9 scale scoring. Results: This study showed that 199 (58%) of the infertile women sufferedfrom depression. There was a statistically significant association with socio economical statuswhile no significant association was detected with age of women, duration of infertility andeducational status. Conclusion: We found a high prevalence of depression among infertilewomen. Depression was more among women belonging to higher socioeconomic class.