Aggressive angiomyxoma is a rare, locally infiltrative mesenchymal tumor found usually in women of reproductive age group. It is a slow-growing, low-grade neoplasm involving the pelvis and perineum with a high risk for local recurrence. Mesenchymal tumors like these present a diagnostic dilemma because a wide variety of them exhibit many overlapping clinical and histological features, requiring the help of immunohistochemistry for diagnostic confirmation. Recurrence even after complete surgical excision is one of the unique characteristics of Aggressive angiomyxoma, which otherwise is a non-malignant tumor. We present a case of a 40 year old female with a huge pedunculated swelling in the vulva, which was suspected to be a fibroepithelial polyp/lipoma on clinical examination and was finally diagnosed as aggressive angiomyxoma after complete work up.

Germ cell tumors account for a majority of all ovarian tumors. Ninety five percent of germ cell tumors are dermoid cysts (Mature cystic teratoma). Carcinomas arising from mature cystic teratoma are quite rare. The most common malignancy being Squamous cell carcinoma (75%). In the present study we report a case of Squamous cell carcinoma arising in a mature cystic teratoma. A 45 year old female presented with mass in abdomen, pain abdomen and dysuria since one month. Total abdominal hysterectomy with bilateral salpingo-opherectomy was done. Histopathology showed well differentiated invasive squamous cell carcinoma arising in the background of mature cystic teratoma (dermoid cyst). Purpose of this report was to create awareness among practitioners to consider this possibility in dermoid cysts of large size in older patients.

No abstract