The CSEM method, which is frequently used as a risk-reduction tool in hydrocarbon exploration, is finally moving to a new frontier: reservoir monitoring and surveillance. In the present work, we present a CSEM time-lapse interpretation workflow. One essential aspect of our workflow is the demonstration of the linear relationship between the anomalous transverse resistance, an attribute extracted from CSEM data inversion, and the SoPhiH attribute, which is estimated from fluid-flow simulators. Consequently, it is possible to reliably estimate SoPhiH maps from CSEM time-lapse surveys using such a relationship. We demonstrate our workflow’s effectiveness in the mature Marlim oilfield by simulating the CSEM time-lapse response after 30 and 40 years of seawater injection and detecting the remaining sweet spots in the reservoir. The Marlim reservoirs are analogous to several turbidite reservoirs worldwide, which can also be appraised with the proposed workflow. The prediction of SoPhiH maps by using CSEM data inversion can significantly improve reservoir time-lapse characterization.