As part of a search for new sustainable plant sources of valuable compounds, the EtOAc extract of the discarded calyces of Physalis peruviana fruit was selected for its significant antiaging activity. Eight new sucrose esters (SEs), named peruvioses F-M (1-8), along with three known SEs, peruvioses A (9), peruviose B (10), and nicandrose D (11), were isolated. Their structures were elucidated by comprehensive analyses of their NMR and MS data. A global fragmentation pattern of these SEs was established from their MS data. The SE extract (SEE) at a concentration of 0.5 mg L upregulated multiple skin-aging biomarkers, namely, collagen I, elastin, and fibrillin-1, in aged normal human dermal fibroblast cells. A 36% increase in collagen I was observed. The elastin and fibrillin-1 contents were fully recovered, and an increase of at least 10% in the production of elastin was observed.

Essential oils and CO2 extracts of Timur (Zanthoxylum armatum DC syn. Zanthoxylum alatum Hemsl.) from fruits cropped in the Nepalese districts Surkhet, Jajarkot and Salyan from 2012 to 2015 were analysed to explain their typical odour and characterize their volatile profile. Best extraction conditions to ensure the right balance of the terpenic fresh notes compared with the sulphury fruity character were obtained with milled fruits and CO2 extraction. Volatile composition allowed supplying zones discrimination. Among more than 130 volatile constituents, identified by GC–MS and quantified by GC‐FID with the use of predicted relative response factors, only 20 were found to have an odour impact by GC‐O using a hybrid methodology between detection frequency and time intensity methods. Limonene, α‐pinene and myrcene explain the terpenic notes. Linalool, citronellal, 6‐methyl heptanal and octanal bring the fatty and aldehydic tone. The spicy facet is linked to (E)‐methyl cinnamate and (Z)‐ethyl cinnamate. 4‐mercapto‐4‐methylpentan‐2‐one, 3‐mercaptohexanol, 3‐mercaptohexyl acetate and 1‐p‐menthene‐8‐thiol are the key olfactive constituents contributing to the typical tropical and grapefruit odours. Their presence was confirmed using the stable isotope dilution assay and reported for the first time in Timur.