Psoriasis is a dermatological, inflammatory, autoimmune disease with a multifactorial manifestation; however, it is not contagious. The diagnosis involves 2.5% of patients who consulted dermatologists. The research is justified due to reports of low efficacy in controlling the disease, side effects and toxicity, interfering with quality of life. The study aimed to conduct a literature review on psoriasis and its treatments. There are several therapeutic protocols for the treatment of psoriasis, which are chosen according to the severity of the clinical case. Topical therapies are employed in early cases while systemic therapies are used in severe cases. Associated phototherapy reduces treatment time and the adverse effects of topical therapies alone, and yields good results. Among the innovative drugs, immunobiologicals such as adalimumab and secukinumab stand out, which are being used in the prescription of the unified health system and demonstrate the fastest and best results in controlling the pathology.
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