Hemangiopericytoma is a rare mesenchymal tumor, considered as a subtype of soft tissue sarcomas with an incidence of 3.77/10.000.000 cases. Intracranial hemangiopericytomas account for less than 1% of all primary tumors of the central nervous system. Due to the lack of data available regarding this disease, national and international research provides information derived from retrospective case series and phase I and phase II studies. This is a case report of a young adult diagnosed with intracranial hemangiopericytoma in 2012 with a history of multiple recurrences and therapeutic approaches, assisted in a public health center in southeastern Brazil. Among the treatment options given to the patient, there are surgery, radiotherapy, and systemic chemotherapy (including alkylating and anthracyclines agents). Systemic therapy usually is offered after multiple recurrences or in a metastatic setting; although it increases progression-free survival, there is not enough data on objective response rate and does not yield increased overall survival.

Wilson's Disease is a rare genetic disorder characterized by a failure in copper metabolism, which promotes copper deposition in both the liver and the brain, which can lead to serious complications if not diagnosed early and treated properly. The present case report exposes a psychotic episode in a patient previously diagnosed with Wilson's Disease and undergoing treatment, who exhibited failures in the follow-up of therapy associated with the excessive use of alcoholic beverages and especially of marijuana cigarettes since adolescence. Therefore, a bibliographical research on the themes was carried out and the discussion permeated about the possible correlations of these factors for the case described. It was concluded that the patient likely had an underdiagnosed psychiatric underlying illness that was exacerbated by accumulation of copper and drug use, causing the psychotic break to occur and thus later allowing for its diagnosis.